catarina silva-costa

Full Name: Ana Catarina da Silva e Costa

Academic Qualification:

• Degree: Biochemistry - FC/UL
  
• Master Degree: Clinical Microbiology - FML/UL
  
• PhD in Microbiology - Faculdade de Medicina, UL
  

Assistant Professor
Instituto de Microbiologia,Faculdade de Medicina de Lisboa, Universidade de Lisboa

My current work focuses the molecular epidemiology of Streptococcus pneumoniae associated with invasive and non-invasive infection. I am particularly interested in the clonal composition of the population of S. pneumoniae isolated in children, with special attention to the invasive infections, and in the evaluation of the impact of the use of pneumococcal conjugate vaccines in this age group, on the serotype distribution and epidemiology of this important pathogen. I am also involved on the molecular diagnosis of complicated pneumonias, also in children, mainly caused by S. pneumoniae.

Emails:

• anacosta_at_fm.ul.pt (replace _at_ by @)
  

C. Silva-Costa, J. A. Carriço, M. Ramirez, and J. Melo-Cristino. 2014. Scarlet fever is caused by a limited number of Streptococcus pyogenes lineages and is associated with the exotoxin genes ssa, speA and speC. Pediatr Infect Dis J. 33(3):306-10. (PMID: 24168973)

A. Friães, Pinto FR, C. Silva-Costa, M. Ramirez, J. Melo-Cristino 2013. Superantigen gene complement of Streptococcus pyogenes - relationship with other typing methods and short-term stability. Eur. J. Clin. Microbiol. Infect. Dis. 32:115-125. (PMID: 22936424)

A. Friães, Pinto FR, C. Silva-Costa, M. Ramirez, J. Melo-Cristino, The Portuguese Group for the Study of Streptococcal Infections. 2012. Group A streptococci clones associated with invasive infections and pharyngitis in Portugal present differences in emm types, superantigen gene content and antimicrobial resistance. BMC Microbiol. 12:280.(PMID: 23181337)

C. Silva-Costa, A. Friães, M. Ramirez, J. Melo-Cristino, The Portuguese Group for the Study of Streptococcal Infections. 2012. Differences between macrolide resistant and susceptible Streptococcus pyogenes: the importance of clonal properties in addition to antibiotic consumption. Antimicrob Agents Chemother. 56:5661–5666. (PMID: 22908153)

Silva-Costa C, Pinto FR, Ramirez M, Melo-Cristino J. and the Portuguese Surveillance Group for the Study of Respiratory Pathogens. 2008. “Decrease in macrolide resistance and clonal instability among Streptococcus pyogenes in Portugal”. Clin. Microbiol. Infect. 14:1152-1159

Carriço, J. A., C. Silva-Costa, J. Melo-Cristino, F. R. Pinto, H. de Lencastre, J. S. Almeida, M. Ramirez. 2006. “Illustration of a common framework for relating multiple typing methods by application to macrolide-resistant Streptococcus pyogenes”. J. Clin. Microbiol. 44:2524-2532

Silva-Costa, C., J. Melo-Cristino and M. Ramirez. 2005. “Identification of macrolide-resistant clones of Streptococcus pyogenes in Portugal”. Clin. Microbiol. Infect. 12:513-518.

Silva-Costa, C., J. Melo-Cristino and M. Ramirez. 2005. Rapid inversion of the prevalences of macrolide resistance phenoypes paralleled by a diversification of T and emm types among Streptococcus pyogenes in Portugal. Antimicrob. Agents Chemother. 49:2109-21