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Sandra Aguiar

Full Name: Sandra Isabel Rodrigues Aguiar

Academic Qualification:

  • Master Degree: Clinical Microbiology - FML/UL
  • Degree: Applied Chemistry, Biotechnology - FCT/UNL

In the last five years I have been interested in the molecular epidemiology of Streptococcus pneumoniae associated with infection. S. pneumoniae is recognized as an important cause of morbidity and mortality especially among pre-school children. Nevertheless this pathogen is also a normal colonizer of the nasopharynx of healthy individuals. The aim of the study is to characterize pneumococcal strains isolated from infections, using several phenotypic and genotypic methodologies, and identify characteristics of more virulent strains for further studies such as host-pathogen interaction.

Emails:

  • siaguiar_at_fm.ul.pt (replace _at_ by @)

Changes in Streptococcus pneumoniae serotypes causing invasive disease with non-universal vaccination coverage of the seven-valent conjugate vaccine. Aguiar SI, Serrano I, Pinto FR, Melo-Cristino J, Ramirez M; Portuguese Surveillance Group for the Study of Respiratory Pathogens. Clin Microbiol Infect. 2008 Sep;14(9):835-43.

Optimal control and analysis of two-color genomotyping experiments using bacterial multistrain arrays. Pinto FR, Aguiar SI, Melo-Cristino J, Ramirez M. BMC Genomics. 2008 May 19;9:230.

The presence of the pilus locus is a clonal property among pneumococcal invasive isolates. Aguiar SI, Serrano I, Pinto FR, Melo-Cristino J, Ramirez M. BMC Microbiol. 2008 Feb 28;8:41.

Emergence of optochin resistance among Streptococcus pneumoniae in Portugal. Aguiar SI, Frias MJ, Santos L, Melo-Cristino J, Ramirez M; Portuguese Surveillance Group For Study Of Respiratory Pathogens. Microb Drug Resist. 2006 Winter;12(4):239-45.

DNA methylase activity as a marker for the presence of a family of phage-like elements conferring efflux-mediated macrolide resistance in streptococci. Figueiredo TA, Aguiar SI, Melo-Cristino J, Ramirez M. Antimicrob Agents Chemother. 2006 Nov;50(11):3689-94. Epub 2006 Sep 5.

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