Differences

This shows you the differences between two versions of the page.

Link to this comparison view

Both sides previous revision Previous revision
Next revision
Previous revision
people:siaguiar [2009/08/28 11:48]
siaguiar
people:siaguiar [2018/02/19 18:06] (current)
Line 1: Line 1:
 ====== Sandra Aguiar ====== ====== Sandra Aguiar ======
-{{:jac2.png|}}+{{:people:​foto_sandra_aguiar_2.jpg|}}
  
 ===== Bio ===== ===== Bio =====
  
-**Full Name**: ​João André Nogueira Custódio Carriço\\ +**Full Name**: ​Sandra Isabel Rodrigues Aguiar\\ 
-**Degrees**:  + 
-  * Applied Chemistry, Biotechnology - FCT/UNL\\+**Academic Qualification**: 
 +  * PhD: Microbiology:​ -FML/UL\\  
 +  * Master Degree: Clinical Microbiology - FML/UL\\ 
 +  * Degree: ​Applied Chemistry, Biotechnology - FCT/UNL\\
    
  
 ===== Current Position ===== ===== Current Position =====
-**PhD Student**\\ ​+**Post-doc ​Student**\\ ​
 [[http://​www.imm.fm.ul.pt/​web/​imm/​molecularmicrobiologyandinfection|Molecular Microbiology and Infection Unit]], [[http://​www.imm.fm.ul.pt/​web/​imm/​home|Instituto de Medicina Molecular]]\\ [[http://​www.imm.fm.ul.pt/​web/​imm/​molecularmicrobiologyandinfection|Molecular Microbiology and Infection Unit]], [[http://​www.imm.fm.ul.pt/​web/​imm/​home|Instituto de Medicina Molecular]]\\
 Instituto de Microbiologia,​[[http://​www.fm.ul.pt/​|Faculdade de Medicina de Lisboa]], Universidade de Lisboa\\ ​ Instituto de Microbiologia,​[[http://​www.fm.ul.pt/​|Faculdade de Medicina de Lisboa]], Universidade de Lisboa\\ ​
  
 ===== Research Interests ===== ===== Research Interests =====
-//​Streptococcus pneumoniae//​\\+ 
 +In the last five years I have been interested in the molecular epidemiology of //​Streptococcus pneumoniae// ​associated with infection. //S. pneumoniae//​ is recognized as an important cause of morbidity and mortality especially among pre-school children. Nevertheless this pathogen is also a normal colonizer of the nasopharynx of healthy individuals. The aim of the study is to characterize pneumococcal strains isolated from infections, using several phenotypic and genotypic methodologies,​ and identify characteristics of more virulent strains for further studies such as host-pathogen interaction.\\
  
  
Line 24: Line 28:
  
 **Emails**: ​ **Emails**: ​
-  * siaguiar_at_fm.ul.pt ​(replace _at_ by @)\\+  * siaguiar@fm.ul.pt ​ 
 +  * siraguiar@gmail.com
  
 ===== Publications ===== ===== Publications =====
 +Use of the 13-valent conjugate vaccine has the potential to eliminate pilus carrying isolates as causes of invasive pneumococcal disease.Aguiar SI, Melo-Cristino J, Ramirez M. 2012.Vaccine 30(37):​5487-90. (PMID:​22749798)
 +
 +Serotype changes in adult invasive pneumococcal infections in Portugal did not reduce the high fraction of potentially vaccine preventable infectionsHorácio,​ A. N., J. Diamantino-Miranda,​ S. I. Aguiar, M. Ramirez, J. Melo-Cristino and the Portuguese Group for the Study of Streptococcal Infections. 2012. Vaccine 30:218-224. (PMID: 22100892) ​
 +
 +Analysis of invasiveness of pneumococcal serotypes and clones circulating in Portugal before widespread use of conjugate vaccines reveals heterogeneous behavior of clones expressing the same serotype.Sá-Leão R., F. Pinto, S. I. Aguiar, S. Nunes, J. A. Carriço, N. Frazão, N. Gonçalves-Sousa,​ J. Melo-Cristino,​ H. de Lencastre, and M. Ramirez. 2011 J. Clin. Microbiol 49:​1369-1375. (PMID: 21270219)
 +
 +Serotypes 1, 7F and 19A became the leading causes of pediatric invasive pneumococcal infections in Portugal after 7 years of heptavalent conjugate vaccine use. [[people:​siaguiar|Aguiar SI]], Brito MJ, Gonçalo-Marques J, Melo-Cristino J, Ramirez M. Vaccine. 2010 Jul 19;​28(32):​5167-73. ​
 +
 +Increase of Denmark14-230 clone as a cause of pneumococcal infection in Portugal within a background of diverse serotype 19A lineages.
 +[[people:​siaguiar|Aguiar SI]], Pinto FR, Nunes S, Serrano I, Melo-Cristino J, Sá-Leão R, Ramirez M, de Lencastre H. 
 +J. Clin. Microbiol. 2009 Oct 28.
 +
 +Changes in Streptococcus pneumoniae serotypes causing invasive disease with non-universal vaccination coverage of the seven-valent conjugate vaccine.
 +[[people:​siaguiar|Aguiar SI]], Serrano I, Pinto FR, Melo-Cristino J, Ramirez M; Portuguese Surveillance Group for the Study of Respiratory Pathogens.
 +Clin Microbiol Infect. 2008 Sep;​14(9):​835-43.
 +
 +Optimal control and analysis of two-color genomotyping experiments using bacterial multistrain arrays.
 +Pinto FR, [[people:​siaguiar|Aguiar SI]], Melo-Cristino J, Ramirez M.
 +BMC Genomics. 2008 May 19;9:230.
 +
 +The presence of the pilus locus is a clonal property among pneumococcal invasive isolates.
 +[[people:​siaguiar|Aguiar SI]], Serrano I, Pinto FR, Melo-Cristino J, Ramirez M.
 +BMC Microbiol. 2008 Feb 28;8:41.
 +
 +Emergence of optochin resistance among Streptococcus pneumoniae in Portugal.
 +[[people:​siaguiar|Aguiar SI]], Frias MJ, Santos L, Melo-Cristino J, Ramirez M; Portuguese Surveillance Group For Study Of Respiratory Pathogens.
 +Microb Drug Resist. 2006 Winter;​12(4):​239-45.
  
 +DNA methylase activity as a marker for the presence of a family of phage-like elements conferring efflux-mediated macrolide resistance in streptococci.
 +Figueiredo TA, [[people:​siaguiar|Aguiar SI]], Melo-Cristino J, Ramirez M.
 +Antimicrob Agents Chemother. 2006 Nov;​50(11):​3689-94. Epub 2006 Sep 5.
  
  • people/siaguiar.1251452887.txt.gz
  • Last modified: 2018/02/19 18:06
  • (external edit)