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people:siaguiar [2012/02/15 23:10]
siaguiar [Publications]
people:siaguiar [2018/02/19 18:06]
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-====== Sandra Aguiar ====== 
-{{:​people:​foto_sandra_aguiar_2.jpg|}} 
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-===== Bio ===== 
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-**Full Name**: Sandra Isabel Rodrigues Aguiar\\ 
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-**Academic Qualification**:​ 
-  * PhD: Microbiology:​ -FML/​UL\\ ​ 
-  * Master Degree: Clinical Microbiology - FML/UL\\ 
-  * Degree: Applied Chemistry, Biotechnology - FCT/UNL\\ 
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-===== Current Position ===== 
-**Post-doc Student**\\ ​ 
-[[http://​www.imm.fm.ul.pt/​web/​imm/​molecularmicrobiologyandinfection|Molecular Microbiology and Infection Unit]], [[http://​www.imm.fm.ul.pt/​web/​imm/​home|Instituto de Medicina Molecular]]\\ 
-Instituto de Microbiologia,​[[http://​www.fm.ul.pt/​|Faculdade de Medicina de Lisboa]], Universidade de Lisboa\\ ​ 
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-===== Research Interests ===== 
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-In the last five years I have been interested in the molecular epidemiology of //​Streptococcus pneumoniae//​ associated with infection. //S. pneumoniae//​ is recognized as an important cause of morbidity and mortality especially among pre-school children. Nevertheless this pathogen is also a normal colonizer of the nasopharynx of healthy individuals. The aim of the study is to characterize pneumococcal strains isolated from infections, using several phenotypic and genotypic methodologies,​ and identify characteristics of more virulent strains for further studies such as host-pathogen interaction.\\ 
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-===== Websites ===== 
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-===== Contacts ===== 
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-**Emails**: ​ 
-  * siaguiar@fm.ul.pt ​ 
-  * siraguiar@gmail.com 
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-===== Publications ===== 
-Serotype changes in adult invasive pneumococcal infections in Portugal did not reduce the high fraction of potentially vaccine preventable infectionsHorácio,​ A. N., J. Diamantino-Miranda,​ S. I. Aguiar, M. Ramirez, J. Melo-Cristino and the Portuguese Group for the Study of Streptococcal Infections. 2012. Vaccine 30:218-224. (PMID: 22100892) ​ 
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-Serotypes 1, 7F and 19A became the leading causes of pediatric invasive pneumococcal infections in Portugal after 7 years of heptavalent conjugate vaccine use. [[people:​siaguiar|Aguiar SI]], Brito MJ, Gonçalo-Marques J, Melo-Cristino J, Ramirez M. Vaccine. 2010 Jul 19;​28(32):​5167-73. ​ 
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-Increase of Denmark14-230 clone as a cause of pneumococcal infection in Portugal within a background of diverse serotype 19A lineages. 
-[[people:​siaguiar|Aguiar SI]], Pinto FR, Nunes S, Serrano I, Melo-Cristino J, Sá-Leão R, Ramirez M, de Lencastre H.  
-J. Clin. Microbiol. 2009 Oct 28. 
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-Changes in Streptococcus pneumoniae serotypes causing invasive disease with non-universal vaccination coverage of the seven-valent conjugate vaccine. 
-[[people:​siaguiar|Aguiar SI]], Serrano I, Pinto FR, Melo-Cristino J, Ramirez M; Portuguese Surveillance Group for the Study of Respiratory Pathogens. 
-Clin Microbiol Infect. 2008 Sep;​14(9):​835-43. 
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-Optimal control and analysis of two-color genomotyping experiments using bacterial multistrain arrays. 
-Pinto FR, [[people:​siaguiar|Aguiar SI]], Melo-Cristino J, Ramirez M. 
-BMC Genomics. 2008 May 19;9:230. 
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-The presence of the pilus locus is a clonal property among pneumococcal invasive isolates. 
-[[people:​siaguiar|Aguiar SI]], Serrano I, Pinto FR, Melo-Cristino J, Ramirez M. 
-BMC Microbiol. 2008 Feb 28;8:41. 
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-Emergence of optochin resistance among Streptococcus pneumoniae in Portugal. 
-[[people:​siaguiar|Aguiar SI]], Frias MJ, Santos L, Melo-Cristino J, Ramirez M; Portuguese Surveillance Group For Study Of Respiratory Pathogens. 
-Microb Drug Resist. 2006 Winter;​12(4):​239-45. 
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-DNA methylase activity as a marker for the presence of a family of phage-like elements conferring efflux-mediated macrolide resistance in streptococci. 
-Figueiredo TA, [[people:​siaguiar|Aguiar SI]], Melo-Cristino J, Ramirez M. 
-Antimicrob Agents Chemother. 2006 Nov;​50(11):​3689-94. Epub 2006 Sep 5. 
  
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