✎ people:anacosta [Molecular Microbiology and Infection Unit]

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====== catarina silva-costa ======
======  ======


===== Bio =====

**Full Name**: Ana Catarina da Silva e Costa\\

**Academic Qualification**: 
  * Degree: Biochemistry - FC/UL\\
  * Master Degree: Clinical Microbiology - FML/UL\\
  * PhD in Microbiology - Faculdade de Medicina, UL\\
 
===== Current Position =====
**Assistant Professor**\\ 
Instituto de Microbiologia,[[http://www.fm.ul.pt/|Faculdade de Medicina de Lisboa]], Universidade de Lisboa\\ 

===== Research Interests =====

My current work focuses the molecular epidemiology of //Streptococcus pneumoniae// associated with invasive and non-invasive infection. I am particularly interested in the clonal composition of the population of //S. pneumoniae// isolated in children , with special attention to the invasive infections, and to evaluate the impact of the use of pneumococcal conjugate vaccines in the serotype distribution and epidemiology of this important pathogen. I am also involved on the molecular diagnosis of complicated pneumonias, also in children, mainly caused by //S. pneumoniae//. 

===== Websites =====


===== Contacts =====

**Emails**: 
  * anacosta_at_fm.ul.pt (replace _at_ by @)\\

===== Publications =====


C. Silva-Costa, J. A. Carriço, M. Ramirez, and J. Melo-Cristino. 2014. Scarlet fever is caused by a limited number of Streptococcus pyogenes lineages and is associated with the exotoxin genes ssa, speA and speC. Pediatr Infect Dis J. 33(3):306-10. (PMID: 24168973)

A. Friães, Pinto FR, C. Silva-Costa, M. Ramirez, J. Melo-Cristino 2013. Superantigen gene complement of Streptococcus pyogenes - relationship with other typing methods and short-term stability. Eur. J. Clin. Microbiol. Infect. Dis. 32:115-125. (PMID: 22936424)

A. Friães, Pinto FR, C. Silva-Costa, M. Ramirez, J. Melo-Cristino, The Portuguese Group for the Study of Streptococcal Infections. 2012. Group A streptococci clones associated with invasive infections and pharyngitis in Portugal present differences in emm types, superantigen gene content and antimicrobial resistance. BMC Microbiol. 12:280.(PMID: 23181337)

C. Silva-Costa, A. Friães, M. Ramirez, J. Melo-Cristino, The Portuguese Group for the Study of Streptococcal Infections. 2012. Differences between macrolide resistant and susceptible Streptococcus pyogenes: the importance of clonal properties in addition to antibiotic consumption. Antimicrob Agents Chemother. 56:5661–5666. (PMID: 22908153)

Silva-Costa C, Pinto FR, Ramirez M, Melo-Cristino J. and the Portuguese Surveillance Group for the Study of Respiratory Pathogens. 2008. “Decrease in macrolide resistance and clonal instability among Streptococcus pyogenes in Portugal”. Clin. Microbiol. Infect. 14:1152-1159

Carriço, J. A., C. Silva-Costa, J. Melo-Cristino, F. R. Pinto, H. de Lencastre, J. S. Almeida, M. Ramirez. 2006. “Illustration of a common framework for relating multiple typing methods by application to macrolide-resistant Streptococcus pyogenes”. J. Clin. Microbiol. 44:2524-2532

Silva-Costa, C., J. Melo-Cristino and M. Ramirez. 2005. “Identification of macrolide-resistant clones of Streptococcus pyogenes in Portugal”. Clin. Microbiol. Infect. 12:513-518.

Silva-Costa, C., J. Melo-Cristino and M. Ramirez. 2005. Rapid inversion of the prevalences of macrolide resistance phenoypes paralleled by a diversification of T and emm types among Streptococcus pyogenes in Portugal. Antimicrob. Agents Chemother. 49:2109-21