====== Ana Friães ====== {{:people:ana.jpg|}} ===== Bio ===== **Full Name**: Ana Isabel de Aquino Friães\\ **Degrees**: * Applied Chemistry, Biotechnology - FCT/UNL\\ * MSc in Biotechnology - FCT/UNL\\ * PhD in Microbiology - Faculdade de Medicina, UL\\ ===== Current Position ===== **Assistant Professor**\\ [[http://www.imm.fm.ul.pt/web/imm/molecularmicrobiologyandinfection|Molecular Microbiology and Infection Unit]], [[http://www.imm.fm.ul.pt/web/imm/home|Instituto de Medicina Molecular]]\\ Instituto de Microbiologia,[[http://www.fm.ul.pt/|Faculdade de Medicina de Lisboa]], Universidade de Lisboa\\ ===== Research Interests ===== Microbiology, Group A Streptococcus epidemiology, pathogenesis, and virulence factors; molecular typing methods.\\ ===== Contacts ===== **Emails**: * afriaes_at_fm.ul.pt (replace _at_ by @)\\ ===== Publications ===== A. Friães, J.P. Lopes, J. Melo-Cristino, M. Ramirez, the Portuguese Group for the Study of Streptococcal Infections. 2013. Changes in //Streptococcus pyogenes// causing invasive disease in Portugal: Evidence for superantigen gene loss and acquisition. Int. J. Med. Microbiol. 303:505-513 C. Gouveia, A. Friães, M. Cassiano-Neves, J. Melo-Cristino, M. Ramirez. 2013. MRSA and PVL positive //Staphylococcus aureus// are rarely found in community-acquired osteoarticular infections in children in Portugal, a country with high MRSA prevalence. Online Int. J. Micr. Res. 1:20–24. A. Friães, F. R. Pinto, C. Silva-Costa, M. Ramirez, J. Melo-Cristino. 2013. Superantigen gene complement of //Streptococcus pyogenes//-relationship with other typing methods and short-term stability. Eur. J. Clin. Microbiol. Infect. Dis. 32:115–125. A. Friães, F. R. Pinto, C. Silva-Costa, M. Ramirez, J. Melo-Cristino, The Portuguese Group for the Study of Streptococcal Infections. 2012. Group A streptococci clones associated with invasive infections and pharyngitis in Portugal present differences in //emm// types, superantigen gene content and antimicrobial resistance. BMC Microbiol. 12:280. C. Silva-Costa, A. Friães, M. Ramirez, J. Melo-Cristino, The Portuguese Group for the Study of Streptococcal Infections. 2012. Differences between macrolide resistant and susceptible //Streptococcus pyogenes//: the importance of clonal properties in addition to antibiotic consumption. Antimicrob. Agents Chemother. 56:5661–5666 J. Melo-Cristino, L. Santos, C. Silva-Costa, A. Friães, M. D. Pinho, M. Ramirez. 2010. The Viriato Study: Update on antimicrobial resistance of microbial pathogens responsible for community-acquired respiratory tract infections in Portugal. Paediatr. Drugs 12:11-17. A. Friães, M. Ramirez, J. Melo-Cristino, The Portuguese Group for the Study of Streptococcal Infections. 2007. Nonoutbreak surveillance of group A streptococci causing invasive disease in Portugal identified internationally disseminated clones among members of a genetically heterogeneous population. J. Clin. Microbiol. 45:2044–2047. J. Gonçalves, A. Friães, L. Moura. 2007. Congenital adrenal hyperplasia: focus on the molecular basis of 21-hydroxylase deficiency. Expert Rev. Mol. Med. 9:1-23. A. Friães, A. T. Rêgo, J. M. Aragüés, L. F. Moura, A. Mirante, M. R. Mascarenhas, T. T. Kay, L. A. Lopes, J. C. Rodrigues, S. Guerra, T. Dias, A. G. Teles, J. Gonçalves. 2006. //CYP21A2// mutations in Portuguese patients with congenital adrenal hyperplasia: Identification of two novel mutations and characterization of four different partial gene conversions. Mol. Genet. Metab. 88:58-65.