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| * Applied Chemistry, Biotechnology - FCT/UNL\\ | * Applied Chemistry, Biotechnology - FCT/UNL\\ | ||
| * MSc in Biotechnology - FCT/UNL\\ | * MSc in Biotechnology - FCT/UNL\\ | ||
| + | * PhD in Microbiology - Faculdade de Medicina, UL\\ | ||
| ===== Current Position ===== | ===== Current Position ===== | ||
| - | **Teaching Assistant**\\ | + | **Assistant Professor**\\ |
| [[http://www.imm.fm.ul.pt/web/imm/molecularmicrobiologyandinfection|Molecular Microbiology and Infection Unit]], [[http://www.imm.fm.ul.pt/web/imm/home|Instituto de Medicina Molecular]]\\ | [[http://www.imm.fm.ul.pt/web/imm/molecularmicrobiologyandinfection|Molecular Microbiology and Infection Unit]], [[http://www.imm.fm.ul.pt/web/imm/home|Instituto de Medicina Molecular]]\\ | ||
| Instituto de Microbiologia,[[http://www.fm.ul.pt/|Faculdade de Medicina de Lisboa]], Universidade de Lisboa\\ | Instituto de Microbiologia,[[http://www.fm.ul.pt/|Faculdade de Medicina de Lisboa]], Universidade de Lisboa\\ | ||
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| ===== Research Interests ===== | ===== Research Interests ===== | ||
| - | Microbiology, Group A Streptococcus epidemiology, pathogenesis, and virulence factors; molecular typing methods\\ | + | Microbiology, Group A Streptococcus epidemiology, pathogenesis, and virulence factors; molecular typing methods.\\ |
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| ===== Publications ===== | ===== Publications ===== | ||
| - | Nonoutbreak surveillance of group A streptococci causing invasive disease in Portugal identified internationally disseminated clones among members of a genetically heterogeneous population. | + | A. Friães, J.P. Lopes, J. Melo-Cristino, M. Ramirez, the Portuguese Group for the Study of Streptococcal Infections. 2013. Changes in //Streptococcus pyogenes// causing invasive disease in Portugal: Evidence for superantigen gene loss and acquisition. Int. J. Med. Microbiol. 303:505-513 |
| - | __Friães A__, Ramirez M, Melo-Cristino J, Portuguese Group for the Study of Streptococcal Infections. | + | |
| - | Journal of Clinical Microbiology 2007 45(6):2044-2047 | + | C. Gouveia, A. Friães, M. Cassiano-Neves, J. Melo-Cristino, M. Ramirez. 2013. MRSA and PVL positive //Staphylococcus aureus// are rarely found in community-acquired osteoarticular infections in children in Portugal, a country with high MRSA prevalence. Online Int. J. Micr. Res. 1:20–24. |
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| + | A. Friães, F. R. Pinto, C. Silva-Costa, M. Ramirez, J. Melo-Cristino. 2013. Superantigen gene complement of //Streptococcus pyogenes//-relationship with other typing methods and short-term stability. Eur. J. Clin. Microbiol. Infect. Dis. 32:115–125. | ||
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| + | A. Friães, F. R. Pinto, C. Silva-Costa, M. Ramirez, J. Melo-Cristino, The Portuguese Group for the Study of Streptococcal Infections. 2012. Group A streptococci clones associated with invasive infections and pharyngitis in Portugal present differences in //emm// types, superantigen gene content and antimicrobial resistance. BMC Microbiol. 12:280. | ||
| + | |||
| + | C. Silva-Costa, A. Friães, M. Ramirez, J. Melo-Cristino, The Portuguese Group for the Study of Streptococcal Infections. 2012. Differences between macrolide resistant and susceptible //Streptococcus pyogenes//: the importance of clonal properties in addition to antibiotic consumption. Antimicrob. Agents Chemother. 56:5661–5666 | ||
| - | Congenital adrenal hyperplasia: focus on the molecular basis of 21-hydroxylase deficiency. | + | J. Melo-Cristino, L. Santos, C. Silva-Costa, A. Friães, M. D. Pinho, M. Ramirez. 2010. The Viriato Study: Update on antimicrobial resistance of microbial pathogens responsible for community-acquired respiratory tract infections in Portugal. Paediatr. Drugs 12:11-17. |
| - | Gonçalves J, __Friães A__, Moura L. | + | |
| - | Expert Reviews in Molecular Medicine 2007 9(11):1-23 | + | |
| - | CYP21A2 mutations in Portuguese patients with congenital adrenal hyperplasia: Identification of two novel mutations and characterization of four different partial gene conversions. | + | A. Friães, M. Ramirez, J. Melo-Cristino, The Portuguese Group for the Study of Streptococcal Infections. 2007. Nonoutbreak surveillance of group A streptococci causing invasive disease in Portugal identified internationally disseminated clones among members of a genetically heterogeneous population. J. Clin. Microbiol. 45:2044–2047. |
| - | __Friães A__, Rêgo AT, Aragüés JM, Moura LF, Mirante A, Mascarenhas MR, Kay TT, Lopes LA, Rodrigues JC, Guerra S, Dias T, Teles AG, Gonçalves J. | + | |
| - | Molecular Genetics and Metabolism 2006 88(1):58-65 | + | |
| + | J. Gonçalves, A. Friães, L. Moura. 2007. Congenital adrenal hyperplasia: focus on the molecular basis of 21-hydroxylase deficiency. Expert Rev. Mol. Med. 9:1-23. | ||
| + | A. Friães, A. T. Rêgo, J. M. Aragüés, L. F. Moura, A. Mirante, M. R. Mascarenhas, T. T. Kay, L. A. Lopes, J. C. Rodrigues, S. Guerra, T. Dias, A. G. Teles, J. Gonçalves. 2006. //CYP21A2// mutations in Portuguese patients with congenital adrenal hyperplasia: Identification of two novel mutations and characterization of four different partial gene conversions. Mol. Genet. Metab. 88:58-65. | ||